Polynucleotides

Your FAQ’s

Frequently Asked Questions

And guide to procedures

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What it is

Polynucleotides are highly purified fragments of DNA, derived from natural sources and clinically formulated for skin repair.

Once injected, they signal your skin cells to activate healing pathways, increasing collagen, elastin, hydration and overall skin quality.

They are classed as biostimulators  meaning they “wake up” the skin’s own regeneration processes rather than adding volume. 

Treatment Plan & Results

  • Course: Typically 2–3 sessions spaced 2–4 weeks apart

  • Maintenance: Every 6–9 months

  • Results: Gradual and natural, with improvements seen from 2–6 weeks post-treatment

  • Longevity: 6–12 months depending on skin condition and lifestyle

 Your practitioner will inject the polynucleotide gel using a series of tiny, precise injections across the treatment area.

This may include the face, under-eyes, neck, décolletage or hands depending on your goals.

Treatments are quick (usually 20–30 minutes) with minimal downtime  most people resume normal activities the same day.

What to expect

Ideal for those who want subtle, natural improvements across a range of concerns, Improves overall texture, tone, glow and resilience. Strengthens and firms ageing skin. Binds and attracts water at a cellular level, giving long-lasting results. Supports regeneration after acne, scarring, sun damage or inflammation.

Reduces crepiness, fine lines and thin/fragile under-eye skin.Works beautifully alongside Botox, fillers, microneedling and skin boosters. 

FAQs

  • No. Fillers add volume instantly. Polynucleotides stimulate regeneration to improve skin quality, elasticity and hydration over time.

  • Yes. They are highly purified and have been used in medical applications for decades. They are biocompatible and very well-tolerated.


    • Under eyes

    • Face

    • Neck

    • Décolletage

    • Hands

    • Acne scarring areas

    • Crepey or sun-damaged skin

  • Yes — they pair perfectly with injectables, microneedling, peels and professional skincare.

  • Most clients looking for natural rejuvenation are suitable. During your consultation, we will assess your skin and recommend the best plan.

Coastal Aesthetics